Important lab values to check prior to the administration of asparaginase include platelets and:

Important lab values to check prior to the administration of asparaginase include platelets and:

• A. glucose, amylase, LFTs
• B. uric acid, BUN, and specific gravity
• C. glucose, protein, and albumin
• D. sodium, potassium, and magnesium

Answer: (A)

Asparaginase carries risks of pancreatitis, hepatotoxicity, and metabolic disturbances affecting glucose. Before giving the drug, you want labs that flag these specific risks: amylase to screen for pancreatitis, liver function tests to detect hepatotoxicity, and glucose to catch possible hyperglycemia that can occur with pancreatotoxic effects. Platelets are checked because of bleeding risk, but the question focuses on the additional labs that align with asparaginase-specific toxicities. The other lab groups don’t target these particular adverse effects as directly.

Asparaginase carries risks of pancreatitis, hepatotoxicity, and metabolic disturbances affecting glucose. Before giving the drug, you want labs that flag these specific risks: amylase to screen for pancreatitis, liver function tests to detect hepatotoxicity, and glucose to catch possible hyperglycemia that can occur with pancreatotoxic effects. Platelets are checked because of bleeding risk, but the question focuses on the additional labs that align with asparaginase-specific toxicities. The other lab groups don’t target these particular adverse effects as directly.